HEPES is not suitable for fluorescence detection of HClO: a novel probe for HClO in absolute PBS

HEPES is not suitable for fluorescence detection of HClO: a novel probe for HClO in absolute PBS

HEPES is not suitable for fluorescence detection of HClO because it can be oxidized by HClO. A novel probe for HClO, which can selectively and sensitively detect HClO in absolute PBS, was developed on the basis of an oxidation reaction with an azo moiety. Furthermore, it works well in live mouse ima...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2016-04, Vol.52 (28), p.564-566
Hauptverfasser: Xing, Panfei, Gao, Kuo, Wang, Beng, Gao, Jian, Yan, Hui, Wen, Jia, Li, Weisi, Xu, Yongqian, Li, Hongjuan, Chen, Jianxin, Wang, Wei, Sun, Shiguo
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Azo
Buffers
Fluorescence
Fluorescent Dyes - analysis
Fluorescent Dyes - chemistry
HEPES - chemistry
Hypochlorous Acid - analysis
Imaging
Mice
Oxidation
Phosphates - chemistry
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Zusammenfassung:HEPES is not suitable for fluorescence detection of HClO because it can be oxidized by HClO. A novel probe for HClO, which can selectively and sensitively detect HClO in absolute PBS, was developed on the basis of an oxidation reaction with an azo moiety. Furthermore, it works well in live mouse imaging. HEPES is not suitable for fluorescence detection of HClO. A novel probe for HClO was developed in absolute PBS.
ISSN:1359-7345
1364-548X
DOI:10.1039/c6cc00880a