Comorbidities Drive Outcomes for Both Malignancy-Associated and Non–Malignancy-Associated Hemophagocytic Syndrome

Micro-Abstract Secondary hemophagocytic syndrome (SHPS) is a rare syndrome that develops in the context of infection, autoimmune disease, or underlying malignancy, resulting in unregulated activation of the immune system. Through a retrospective analysis of a large inpatient national database and th...

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Veröffentlicht in:	Clinical lymphoma, myeloma and leukemia myeloma and leukemia, 2016-04, Vol.16 (4), p.230-236
Hauptverfasser:	Johnson, Benny, Giri, Smith, Nunnery, Sara E, Wiedower, Eric, Jamy, Omer, Yaghmour, George, Chandler, Jason C, Martin, Mike G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Autoimmune disease Charlson comorbidity index Comorbidity Hematology, Oncology and Palliative Medicine Humans Lymphohistiocytosis, Hemophagocytic - complications Malignancy Middle Aged Organ dysfunction Secondary hemophagocytic syndrome Young Adult
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Zusammenfassung:	Micro-Abstract Secondary hemophagocytic syndrome (SHPS) is a rare syndrome that develops in the context of infection, autoimmune disease, or underlying malignancy, resulting in unregulated activation of the immune system. Through a retrospective analysis of a large inpatient national database and the Charlson comorbidity index (CCI), we identified novel predictors of mortality among 276 hospitalizations in adults with SHPS.
ISSN:	2152-2650 2152-2669
DOI:	10.1016/j.clml.2016.01.002