Longitudinal magnetic resonance imaging study shows progressive pyramidal and callosal damage in Friedreich's ataxia

ABSTRACT Introduction Spinal cord and peripheral nerves are classically known to be damaged in Friedreich's ataxia, but the extent of cerebral involvement in the disease and its progression over time are not yet characterized. The aim of this study was to evaluate longitudinally cerebral damage...

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Veröffentlicht in:	Movement disorders 2016-01, Vol.31 (1), p.70-78
Hauptverfasser:	Rezende, Thiago J.R., Silva, Cynthia B., Yassuda, Clarissa L., Campos, Brunno M., D'Abreu, Anelyssa, Cendes, Fernando, Lopes-Cendes, Iscia, França Jr, Marcondes C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age of Onset Corpus Callosum - pathology Cross-Sectional Studies Diffusion Tensor Imaging Disease Progression DTI Female Freesurfer Friedreich Ataxia - pathology Friedreich's ataxia Gray Matter - pathology Humans Image Processing, Computer-Assisted Longitudinal Studies Male Movement disorders MRI Pyramidal Tracts - pathology Retrospective Studies Severity of Illness Index Statistics as Topic VBM Young Adult
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