Preferential Apoptosis of HIV-1-Specific CD4 super(+) T Cells

In contrast to other viral infections such as CMV, circulating frequencies of HIV-1-specific CD4 super(+) T cells in peripheral blood are quantitatively diminished in the majority of HIV-1-infected individuals. One mechanism for this quantitative defect is preferential infection of HIV-1-specific CD...

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Veröffentlicht in:The Journal of immunology (1950) 2005-02, Vol.174 (4), p.2196-2204
Hauptverfasser: Yue, Feng Yun, Kovacs, Colin M, Dimayuga, Rowena C, Gu, Xiao Xiao Jenny, Parks, Paul, Kaul, Rupert, Ostrowski, Mario A
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Sprache:eng
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Zusammenfassung:In contrast to other viral infections such as CMV, circulating frequencies of HIV-1-specific CD4 super(+) T cells in peripheral blood are quantitatively diminished in the majority of HIV-1-infected individuals. One mechanism for this quantitative defect is preferential infection of HIV-1-specific CD4 super(+) T cells, although
ISSN:0022-1767