Clinical implications of human papilloma virus and other biologic markers in nasopharyngeal cancer

Highlights • The study identified relatively low expression of HPV DNA overall. • P16 expression was identified in more than half of nasopharyngeal cancer patients. • P16 expression correlated with improved nasopharyngeal cancer-specific survival. • P16 may be a prognostic marker for nasopharyngeal...

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Veröffentlicht in:	Oral oncology 2016-04, Vol.55, p.e7-e10
Hauptverfasser:	Kang, Hyunmo, Kwon, Minsu, Park, Jung Je, Kim, Jin Pyeong, Woo, Seung Hoon, Ahn, Seong-Ki, Lee, Jong Sil, Seo, Ji Hyun, Hwa, Jeong Seok
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomarkers, Tumor - metabolism Female Genes, p16 Genes, p53 Hematology, Oncology and Palliative Medicine Herpesvirus 4, Human - isolation & purification Humans Male Middle Aged Nasopharyngeal Neoplasms - virology Otolaryngology Papillomaviridae - isolation & purification Papillomavirus Infections - virology Receptor, Epidermal Growth Factor Survival Rate Young Adult
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Zusammenfassung:	Highlights • The study identified relatively low expression of HPV DNA overall. • P16 expression was identified in more than half of nasopharyngeal cancer patients. • P16 expression correlated with improved nasopharyngeal cancer-specific survival. • P16 may be a prognostic marker for nasopharyngeal cancer.
ISSN:	1368-8375 1879-0593
DOI:	10.1016/j.oraloncology.2016.02.002