Impact of comorbidities and gender on the use of coronary interventions in patients with high-risk non-ST-segment elevation acute coronary syndrome

Objectives To determine the impact of gender and comorbidity on use of coronary interventions in patients diagnosed with high‐risk non‐ST‐segment acute coronary syndrome (NSTEACS). Background Guidelines recommend the use of coronary angiography for all patients diagnosed with NSTEACS with high‐risk features, except in the presence of severe comorbidities. However, little is understood about the relationship between gender, comorbidity, and the use of coronary interventions. Methods Retrospective analyses of the Victorian Admitted Episodes Data Set (VAED) including all patients diagnosed with NSTEACS with high‐risk features on their first admission for ACS between June 2007 and July 2009. Hierarchical logistic regression models and correspondence analyses were used to understand the relationship between gender, comorbidities, and the use of coronary interventions. Results Out of 16,771 NSTEACS patients with high‐risk features, 6,338 (38%) were female. Females were older than males (aged ≥75: 62% vs 39%, p