Influence of underlying substrate on atrial tachyarrhythmias after pulmonary vein isolation

Background Recurrent atrial tachyarrhythmias occur as a result of residual atrial arrhythmogenic substrates after atrial fibrillation (AF) ablation. In patients with AF, electrograms with reduced amplitudes indicate diseased myocardium. Objective The purpose of this study was to investigate the asso...

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Veröffentlicht in:	Heart rhythm 2016-04, Vol.13 (4), p.870-878
Hauptverfasser:	Masuda, Masaharu, MD, Fujita, Masashi, MD, PhD, Iida, Osamu, MD, Okamoto, Shin, MD, Ishihara, Takayuki, MD, Nanto, Kiyonori, MD, Kanda, Takashi, MD, Shiraki, Tatsuya, MD, Sunaga, Akihiro, MD, Matsuda, Yasuhiro, MD, Uematsu, Masaaki, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Atrial fibrillation Atrial Fibrillation - physiopathology Atrial Fibrillation - surgery Atrial tachycardia Body Surface Potential Mapping Cardiovascular Catheter Ablation - methods Female Follow-Up Studies Heart Conduction System - physiopathology Heart Conduction System - surgery Humans Inducibility Low-voltage area Male Middle Aged Postoperative Period Prospective Studies Pulmonary Veins - surgery Substrate Time Factors Treatment Outcome
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Zusammenfassung:	Background Recurrent atrial tachyarrhythmias occur as a result of residual atrial arrhythmogenic substrates after atrial fibrillation (AF) ablation. In patients with AF, electrograms with reduced amplitudes indicate diseased myocardium. Objective The purpose of this study was to investigate the association between the distribution of low-voltage areas and the type of induced atrial tachyarrhythmias. Methods Our prospective observational study enrolled 152 consecutive AF patients scheduled for an initial ablation (46% persistent AF). After pulmonary vein isolation, voltage mapping was performed during sinus rhythm, and regions with reduced electrogram amplitudes (
ISSN:	1547-5271 1556-3871
DOI:	10.1016/j.hrthm.2015.12.029