Quantiferon-Gold Tuberculosis Test Cannot Detect Latent Tuberculosis in Patients With Leprosy

Five of 10 paucibacillary leprosy patients were Quantiferon Gold (Q-G) positive with negative chest X-rays. Forty multibacillary leprosy patients were negative. Reports have shown 100% cross-reactivity of ESAT6 and CFP10 between Mycobacterium leprae and Mycobacterium tuberculosis. The Q-G test canno...

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Veröffentlicht in:	Clinical infectious diseases 2015-11, Vol.61 (9), p.1439-1440
Hauptverfasser:	Rendini, Tina, Levis, William
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Bacterial - immunology Bacteria BRIEF REPORTS Cross Reactions Diagnostic Errors Humans Interferon-gamma Release Tests - methods Latent Tuberculosis - diagnosis Leprosy Leprosy - complications Medical tests Mycobacterium leprae - immunology Mycobacterium tuberculosis - immunology Tuberculosis
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Zusammenfassung:	Five of 10 paucibacillary leprosy patients were Quantiferon Gold (Q-G) positive with negative chest X-rays. Forty multibacillary leprosy patients were negative. Reports have shown 100% cross-reactivity of ESAT6 and CFP10 between Mycobacterium leprae and Mycobacterium tuberculosis. The Q-G test cannot detect latent tuberculosis in patients with leprosy.
ISSN:	1058-4838 1537-6591
DOI:	10.1093/cid/civ588