John G. Bartlett: Contributions to the Discovery of Clostridium difficile Antibiotic-Associated Diarrhea

In 1975 John Bartlett began trials investigating the problem of antibiotic-associated diarrhea and pseudomembranous colitis. His work led the discovery of Clostridium difficile and he identified it as the leading cause of hospital-associated infections.

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Bibliographische Detailangaben
Veröffentlicht in:	Clinical infectious diseases 2014-09, Vol.59 (suppl_2), p.S66-S70
1. Verfasser:	Gorbach, Sherwood L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - adverse effects Antibiotics Bacterial Toxins - immunology Bartlett, John G Clostridium Clostridium difficile Clostridium difficile - immunology Colitis Cross Infection - history Cross Infection - microbiology Diarrhea Diarrhea - history Diarrhea - microbiology Drug resistance Enterocolitis, Pseudomembranous - history Enterocolitis, Pseudomembranous - microbiology Epidemiology Gram-positive bacteria History, 20th Century Humans Nosocomial infections Pseudomembranous enterocolitis Relapse Toxins Vascular diseases
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Beschreibung
Zusammenfassung:	In 1975 John Bartlett began trials investigating the problem of antibiotic-associated diarrhea and pseudomembranous colitis. His work led the discovery of Clostridium difficile and he identified it as the leading cause of hospital-associated infections.
ISSN:	1058-4838 1537-6591
DOI:	10.1093/cid/ciu419