Time-based understanding of DLCO and DLNO

Highlights • A new simple physical interpretation of DLCO and DLNO is presented. • It allows for a marked reduction of the dispersion between individuals. • It shows that the conventional correction to DLCO for anaemia is erroneous. • It provides a direct determination of the capillary volume from a...

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Veröffentlicht in:	Respiratory physiology & neurobiology 2016-05, Vol.225, p.48-59
Hauptverfasser:	Kang, Min-Yeong, Sapoval, Bernard
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Alveolar-capillary membrane Blood Cells - metabolism Capillaries - metabolism Capillary volume Carbon Monoxide - metabolism Diffusion DLCO DLNO Female Haematocrit Hemoglobins - metabolism Heterogeneity Humans Male Medical Education Models, Cardiovascular Nitric Oxide - metabolism Oxygen - metabolism Pulmonary Alveoli - metabolism Pulmonary/Respiratory Respiration
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