CT imaging of bone and bone marrow infiltration in malignant melanoma—Challenges and limitations for clinical staging in comparison to 18FDG-PET/CT

Highlights • Disseminated bone marrow involvement is accompanied by high mortality. • The diagnostic value of CT for detection of bone marrow involvement is limited. • PET/CT is recommendable for melanoma patients with obscure elevation of serological markers.

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Bibliographische Detailangaben
Veröffentlicht in:	European journal of radiology 2016-04, Vol.85 (4), p.732-738
Hauptverfasser:	Bier, Georg, Hoffmann, Vera, Kloth, Christopher, Othman, Ahmed E, Eigentler, Thomas, Garbe, Claus, La Fougère, Christian, Pfannenberg, Christina, Nikolaou, Konstantin, Klumpp, Bernhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Anaemia Bone and Bones - diagnostic imaging Bone and Bones - pathology Bone marrow Bone Marrow - diagnostic imaging Bone Marrow - pathology Bone Marrow Neoplasms - diagnosis Bone Neoplasms - diagnosis Computed tomography Female Fluorodeoxyglucose F18 Humans Male Melanoma Melanoma - diagnosis Middle Aged Multimodal Imaging Neoplasm Staging PET/CT Positron-Emission Tomography - methods Radiology Radiopharmaceuticals Reproducibility of Results Retrospective Studies Sensitivity and Specificity Tomography, X-Ray Computed - methods Young Adult
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Beschreibung
Zusammenfassung:	Highlights • Disseminated bone marrow involvement is accompanied by high mortality. • The diagnostic value of CT for detection of bone marrow involvement is limited. • PET/CT is recommendable for melanoma patients with obscure elevation of serological markers.
ISSN:	0720-048X 1872-7727
DOI:	10.1016/j.ejrad.2016.01.012