Effect of duodenal glucose load on blood pressure in type 2 diabetes

Highlights • Postprandial hypotension is defined as fall in BP ≥ 20 mmHg post-meal. • It is common in diabetes, often with serious consequences. • Gastric emptying varies widely (1–4 kcal/min) impacting duodenal nutrient delivery. • The fall in BP is greater at duodenal rate of 4 kcal/min in diabete...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Diabetes research and clinical practice 2016-03, Vol.113, p.38-40
Hauptverfasser:	Marathe, Chinmay S, Horowitz, Michael, Trahair, Laurence G, Bound, Michelle, Checklin, Helen, Lange, Kylie, Rayner, Christopher K, Jones, Karen L
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Pressure - drug effects Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - physiopathology Duodenum - drug effects Endocrinology & Metabolism Gastric emptying Gastric Emptying - drug effects Glucose - pharmacology Heart Rate - drug effects Humans Hypotension - drug therapy Hypotension - physiopathology Intraduodenal glucose Male Middle Aged Postprandial blood pressure Postprandial Period - physiology Sweetening Agents - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • Postprandial hypotension is defined as fall in BP ≥ 20 mmHg post-meal. • It is common in diabetes, often with serious consequences. • Gastric emptying varies widely (1–4 kcal/min) impacting duodenal nutrient delivery. • The fall in BP is greater at duodenal rate of 4 kcal/min in diabetes. • Slowing gastric emptying may help in management of postprandial hypotension.
ISSN:	0168-8227 1872-8227
DOI:	10.1016/j.diabres.2016.01.024