Amantadine Monotherapy of Chronic Hepatitis C Patients Infected with Genotype 1b

We aimed to test the efficacy of amantadine in chronic hepatitis C (CHC) patients infected with genotype 1b. Twenty patients completed treatment with amantadine HCl, 100 mg b.i.d., for 6 months. Non-sustained biochemical improvement was observed without loss of HCV-RNA. We conclude that amantadine m...

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Veröffentlicht in:	Scandinavian journal of infectious diseases 2000, Vol.32 (5), p.575-576
1. Verfasser:	Hakan Senturk, Ali Mert, Meral Akdogan, Fehmi Tabak, Gurkan Basaran, Salih Turkoglu, Gulsen Ozbay, Selim Badur
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Biological and medical sciences Hepatitis C virus Medical sciences Pharmacology. Drug treatments
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Beschreibung
Zusammenfassung:	We aimed to test the efficacy of amantadine in chronic hepatitis C (CHC) patients infected with genotype 1b. Twenty patients completed treatment with amantadine HCl, 100 mg b.i.d., for 6 months. Non-sustained biochemical improvement was observed without loss of HCV-RNA. We conclude that amantadine monotherapy is not effective in CHC.
ISSN:	0036-5548 1651-1980
DOI:	10.1080/003655400458965