Cardiac Magnetic Resonance Reveals Signs of Subclinical Myocardial Inflammation in Asymptomatic HIV-Infected Patients

Cardiac Magnetic Resonance Reveals Signs of Subclinical Myocardial Inflammation in Asymptomatic HIV-Infected Patients

People living with chronic HIV infection are at an increased risk for cardiovascular disease. With this study, we aimed to determine the extent of cardiovascular involvement in asymptomatic HIV-infected patients by a comprehensive cardiac magnetic resonance (CMR) approach. Asymptomatic patients with...

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Veröffentlicht in:Circulation. Cardiovascular imaging 2016-03, Vol.9 (3), p.e004091-e004091
Hauptverfasser: Luetkens, Julian A, Doerner, Jonas, Schwarze-Zander, Carolynne, Wasmuth, Jan-Christian, Boesecke, Christoph, Sprinkart, Alois M, Schmeel, Frederic C, Homsi, Rami, Gieseke, Juergen, Schild, Hans H, Rockstroh, Jürgen K, Naehle, Claas P
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Anti-HIV Agents - therapeutic use
Asymptomatic Diseases
Case-Control Studies
Female
Fibrosis
HIV Infections - complications
HIV Infections - diagnosis
HIV Infections - drug therapy
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Myocarditis - diagnosis
Myocarditis - pathology
Myocarditis - physiopathology
Myocarditis - virology
Myocardium - pathology
Predictive Value of Tests
Prognosis
Prospective Studies
Stroke Volume
Ventricular Function, Left
Viral Load
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Zusammenfassung:People living with chronic HIV infection are at an increased risk for cardiovascular disease. With this study, we aimed to determine the extent of cardiovascular involvement in asymptomatic HIV-infected patients by a comprehensive cardiac magnetic resonance (CMR) approach. Asymptomatic patients with chronic HIV infection undergoing combination antiretroviral therapy (n=28) and control subjects (n=22) underwent CMR. HIV-infected patients were successfully controlled for the disease with a consistent plasma viremia of
ISSN:1941-9651
1942-0080
DOI:10.1161/CIRCIMAGING.115.004091