Oral chronic GVHD outcomes and resource utilization: a subanalysis from the chronic GVHD consortium

Objectives This study evaluated the extent to which oral chronic graft‐versus‐host disease (cGVHD) consensus assessments are predictive of management across institutions with and without oral medicine (OM) centers, and whether ancillary care guidelines are followed within clinical practice. Methods...

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Veröffentlicht in:Oral diseases 2016-04, Vol.22 (3), p.235-240
Hauptverfasser: Yuan, A, Chai, X, Martins, F, Arai, S, Arora, M, Correa, ME, Pidala, J, Cutler, CS, Lee, SJ, Treister, NS
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Sprache:eng
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Zusammenfassung:Objectives This study evaluated the extent to which oral chronic graft‐versus‐host disease (cGVHD) consensus assessments are predictive of management across institutions with and without oral medicine (OM) centers, and whether ancillary care guidelines are followed within clinical practice. Methods Longitudinal oral cGVHD data were ed from the cGVHD Consortium, and additional mouth‐specific management data were analyzed across five transplant centers. Results Seventy‐nine patients with 656 visits were observed for a median of 7.1 months with one visit per follow‐up month. Ancillary therapies for oral cGVHD were prescribed for 67% of patients for a median of 0.46 months (per follow‐up month) at OM centers and 0.78 months at non‐OM centers. Patients treated with ancillary therapy were more likely to have an National Institutes of Health (NIH) mouth score of ≥1 (P 
ISSN:1354-523X
1601-0825
DOI:10.1111/odi.12429