Antimicrobial photodynamic effect of phenothiazinic photosensitizers in formulations with ethanol on Pseudomonas aeruginosa biofilms

Highlights • MB formulations produced more singlet oxygen than TB formulations. • MB/ethanol formulations produced more singlet oxygen than MB/water formulation. • MB/ethanol formulations promoted a statistical reduction of P. aeruginosa. • TB/ethanol formulations promoted no significant reduction o...

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Veröffentlicht in:	Photodiagnosis and photodynamic therapy 2016-03, Vol.13, p.291-296
Hauptverfasser:	Prochnow, Emilia Pithan, Martins, Maritieli Righi, Campagnolo, Cibele Bruno, Santos, Roberto Christ, Villetti, Marcos Antonio, Kantorski, Karla Zanini
Format:	Artikel
Sprache:	eng
Schlagworte:	Biofilms - drug effects Biofilms - growth & development Cell Survival - drug effects Cell Survival - physiology Drug Compounding - methods Ethanol - chemistry Hematology, Oncology and Palliative Medicine Internal Medicine Laser in dentistry Microbiology Phenothiazines - administration & dosage Phenothiazines - chemistry Photochemotherapy - methods Photodynamic inactivation Photodynamic therapy (PDT) Photosensitizing Agents - administration & dosage Photosensitizing Agents - chemistry Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - physiology Singlet Oxygen - chemistry Singlet Oxygen - radiation effects Sterilization - methods
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Zusammenfassung:	Highlights • MB formulations produced more singlet oxygen than TB formulations. • MB/ethanol formulations produced more singlet oxygen than MB/water formulation. • MB/ethanol formulations promoted a statistical reduction of P. aeruginosa. • TB/ethanol formulations promoted no significant reduction of P. aeruginosa.
ISSN:	1572-1000 1873-1597
DOI:	10.1016/j.pdpdt.2015.08.008