Induction chemotherapy prior to surgery with or without postoperative radiotherapy for oral cavity cancer patients: Systematic review and meta-analysis

Highlights • This is a systematic review and meta-analysis involving oral cavity cancer patients only. • Induction chemotherapy before surgery did not improve clinical outcomes. • There may be a survival benefit from induction chemotherapy in the cN2 subgroup.

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Bibliographische Detailangaben
Veröffentlicht in:	European journal of cancer (1990) 2015-11, Vol.51 (17), p.2596-2603
Hauptverfasser:	Marta, Gustavo N, Riera, Rachel, Bossi, Paolo, Zhong, Lai-ping, Licitra, Lisa, Macedo, Cristiane R, de Castro, Gilberto, Carvalho, André L, William, William N, Kowalski, Luis Paulo
Format:	Artikel
Sprache:	eng
Schlagworte:	Clinical Trials, Phase III as Topic Combined Modality Therapy Hematology, Oncology and Palliative Medicine Humans Induction chemotherapy Induction Chemotherapy - methods Mouth Neoplasms - drug therapy Mouth Neoplasms - radiotherapy Mouth Neoplasms - surgery Neoplasms Oral cavity Postoperative Period Preoperative Period Prognosis Radiotherapy Randomized Controlled Trials as Topic Surgery Survival Survival Analysis Treatment Treatment Outcome
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Beschreibung
Zusammenfassung:	Highlights • This is a systematic review and meta-analysis involving oral cavity cancer patients only. • Induction chemotherapy before surgery did not improve clinical outcomes. • There may be a survival benefit from induction chemotherapy in the cN2 subgroup.
ISSN:	0959-8049 1879-0852
DOI:	10.1016/j.ejca.2015.08.007