A Dispersion-Dominated Chromogenic Strategy for Colorimetric Sensing of Glutathione at the Nanomolar Level Using Gold Nanoparticles

A Dispersion-Dominated Chromogenic Strategy for Colorimetric Sensing of Glutathione at the Nanomolar Level Using Gold Nanoparticles

A dispersion‐dominated chromogenic strategy for glutathione sensing is developed. Glutathione prevents the aggregation of arginine‐modified gold nanoparticles via mercury–thiol interaction, which allows for glutathione sensing at the nanomolar level (10.9 × 10−9 m) with facile operation and naked‐ey...

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Veröffentlicht in:Small (Weinheim an der Bergstrasse, Germany) Germany), 2015-11, Vol.11 (41), p.5510-5514
Hauptverfasser: Xianyu, Yunlei, Xie, Yangzhouyun, Wang, Nuoxin, Wang, Zhuo, Jiang, Xingyu
Format: Artikel
Sprache:eng
Schlagworte:
Agglomeration
cancer cells
Chromogenic Compounds - chemical synthesis
colorimetric sensors
Colorimetry
Colorimetry - instrumentation
Detection
Equipment Design
Equipment Failure Analysis
Glutathione
Glutathione - analysis
Glutathione - chemistry
Gold
Gold - chemistry
gold nanoparticles
mercury
Mercury - chemistry
Metal Nanoparticles - chemistry
Metal Nanoparticles - ultrastructure
Microchemistry - instrumentation
Nanoparticles
Nanostructure
Nanotechnology
Reproducibility of Results
Sensitivity and Specificity
Strategy
Sulfhydryl Compounds - chemistry
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Zusammenfassung:A dispersion‐dominated chromogenic strategy for glutathione sensing is developed. Glutathione prevents the aggregation of arginine‐modified gold nanoparticles via mercury–thiol interaction, which allows for glutathione sensing at the nanomolar level (10.9 × 10−9 m) with facile operation and naked‐eye readout.
ISSN:1613-6810
1613-6829
DOI:10.1002/smll.201500903