Time–frequency analysis of simultaneous measurements of electroencephalograms, electromyograms, and mechanical tremor under Parkinson disease

A method for the analysis of the time–frequency dynamics of the background brain activity is proposed and used to reveal three main features of the early-stage Parkinson disease (PD): hemispheric asymmetry of the time–frequency characteristics of electroencephalogram in the central lead of the motor zone of the cerebral cortex, generation of the rhythm of electroencephalogram in these leads in a frequency interval of 4–6 Hz and its correlation with electromyograms and mechanical tremor of contralateral limbs upon Parkinsonian tremor, and disorganization of the dominant rhythm corresponding to the general concept of the disorganization of various systems under PD.