A Bio-inspired Approach for Chromophore Communication: Ligand-to-Ligand and Host-to-Guest Energy Transfer in Hybrid Crystalline Scaffolds

Efficient multiple‐chromophore coupling in a crystalline metal–organic scaffold was achieved by mimicking a protein system possessing 100 % energy‐transfer (ET) efficiency between a green fluorescent protein variant and cytochrome b562. The two approaches developed for ET relied on the construction of coordination assemblies and host–guest coupling. Based on time‐resolved photoluminescence measurements in combination with calculations of the spectral overlap function and Förster radius, we demonstrated that both approaches resulted in a very high ET efficiency. In particular, the observed ligand‐to‐ligand ET efficiency value was the highest reported so far for two distinct ligands in a metal–organic framework. These studies provide important insights for the rational design of crystalline hybrid scaffolds consisting of a large ensemble of chromophore molecules with the capability of directional ET. Energie‐Flippern: Das effiziente Kuppeln von Chromophoren in einem Proteingerüst ließ sich durch den Einbau von Chromophoren in Metall‐organische Gerüstverbindungen (MOFs) nachahmen. Die Effizienz des Ligand‐Ligand‐Energietransfers (ET), die auf der Grundlage experimenteller zeitaufgelöster Photolumineszenzdaten berechnet wurde, ist die höchste, die bislang zwischen zwei in einer MOF‐Matrix koordinativ immobilisierten Liganden erreicht wurde.