Microbial transformation of antimalarial terpenoids

The fungal and bacterial transformation of terpenoids derived from plant essential oils, especially the sesquiterpenoid artemisinin from Artemisia annua, has produced several new candidate drugs for the treatment of malaria. Obtaining new derivatives of terpenoids, including artemisinin derivatives...

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Veröffentlicht in:	Biotechnology advances 2012-11, Vol.30 (6), p.1516-1523
Hauptverfasser:	Parshikov, Igor A., Netrusov, Alexander I., Sutherland, John B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimalarials - chemistry Antimalarials - metabolism Artemisia annua Artemisinin Bacteria Bacteria - metabolism Biotechnology Biotransformation chemistry Derivatives drugs Essential oils Fungi Fungi - metabolism Malaria Microorganisms Plants (organisms) Plasmodium Terpenes Terpenes - chemistry Terpenes - metabolism Transformations
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