Implication for the regulation of catabolism drawn from the single insulin-like growth factor binding domain protein (SIBD) gene in the mud crab, Scylla paramamosain

Highlights • A full-length cDNA of SIBD ( Sp-SIBD ) was firstly isolated from the mud crab. • Transcripts of Sp-SIBD were mainly localized to the B cell of the hepatopancreas. • Sp-SIBD expression was strongly up-regulated in response to various stresses. • Sp-SIBD might sequester insulin-like peptides to inhibit energy-expensive growth. • SIBD promise to be insulin-like peptide-specific binding protein in invertebrates.