Alkenes with antioxidative activities from Murraya koenigii (L.) Spreng

[Display omitted] Four new alkenes (1–4), and six known alkenes (5–12) were isolated from Murraya koenigii (L.) Spreng. Their structures were elucidated on the basis of spectroscopic analyses and references. Compounds (1–12) were evaluated for antioxidative activities. Among them, compounds 1, 2, 4,...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2016-02, Vol.26 (3), p.799-803
Hauptverfasser:	Ma, Qin-Ge, Xu, Kun, Sang, Zhi-Pei, Wei, Rong-Rui, Liu, Wen-Min, Su, Ya-Lun, Yang, Jian-Bo, Wang, Ai-Guo, Ji, Teng-Fei, Li, Lu-Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkene Alkenes - chemistry Alkenes - isolation & purification Antioxidants - chemistry Antioxidants - isolation & purification Antioxidative activity Circular Dichroism Inhibitory Concentration 50 Magnetic Resonance Spectroscopy Molecular Conformation Murraya Murraya - chemistry Murraya - metabolism Murraya koenigii Plant Extracts - chemistry Plant Leaves - chemistry Plant Leaves - metabolism
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Zusammenfassung:	[Display omitted] Four new alkenes (1–4), and six known alkenes (5–12) were isolated from Murraya koenigii (L.) Spreng. Their structures were elucidated on the basis of spectroscopic analyses and references. Compounds (1–12) were evaluated for antioxidative activities. Among them, compounds 1, 2, 4, and 7 exhibited significant antioxidative activities using 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay with IC50=21.4–49.5μM. The known compounds (5–12) were isolated from this plant for the first time.
ISSN:	0960-894X 1464-3405
DOI:	10.1016/j.bmcl.2015.12.091