Hospital-based register of stroke in the Molise Region: focus on main subtypes of stroke. Years 2009–2013

We determined incidence and intra-hospital mortality rate of stroke in Molise, Italy, to provide information for planning regional healthcare facilities and to ameliorate stroke management in this region. This study is part of the "Rete Molisana dell’Ictus Cerebrale (REMOLIC)” study, a population-based Cerebrovascular Registry in Molise, from 2009 to 2013, with a cold pursuit approach. The crude annual incidence rates for total stroke per 100,000 inhabitants, notified by hospital discharge records, were 198 for 2009, 185 for 2010, 169 for 2011, and 176 for both 2012 and 2013. There was a significant decrease in risk in the years 2011–2013 [RR 2011 vs. 2009 : 0.85 (0.76–0.98), RR 2012 vs. 2009 : 0.89 (0.79–0.99), RR 2013 vs. 2009 : 0.89 (0.79–0.99)] as compared with 2009. For the year 2010, after adjustment to the Italian, European, and world populations, the overall incidence rates were 165, 134, and 67 per 100,000/year, respectively. Similar trends were found when men and women were analyzed separately. In the average, 20.8 % of subjects admitted for a cerebrovascular accident died during the hospitalization, among these 93.5 % in the first 28 days. The duration of hospital stay was constant in the years (2009–2012), except during 2013, where there was a significant decrease in the average ( p