Pathophysiological role of osteopontin and angiotensin II in atherosclerosis

Pathophysiological role of osteopontin and angiotensin II in atherosclerosis

•This review includes some new mechanisms of Atherosclerosis.•In the context of atherosclerosis, OPN and Ang II is generally regarded as a proinflammatory and proatherogenic molecule.•The most highlight is we reviewed the mechanism that OPN modulates Ang II-induced inflammation in Atherosclerosis....

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Veröffentlicht in:Biochemical and biophysical research communications 2016-02, Vol.471 (1), p.5-9
Hauptverfasser: Ding, Yulong, Chen, Jianing, Cui, Guangying, Wei, Yingfeng, Lu, Chong, Wang, Lin, Diao, Hongyan
Format: Artikel
Sprache:eng
Schlagworte:
Angiotensin II
Angiotensin II - immunology
Animals
Atherosclerosis
Atherosclerosis - immunology
Humans
Immunologic Factors - immunology
Models, Cardiovascular
Models, Immunological
Osteopontin
Osteopontin - immunology
Vasculitis - immunology
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Beschreibung
Zusammenfassung:•This review includes some new mechanisms of Atherosclerosis.•In the context of atherosclerosis, OPN and Ang II is generally regarded as a proinflammatory and proatherogenic molecule.•The most highlight is we reviewed the mechanism that OPN modulates Ang II-induced inflammation in Atherosclerosis.
ISSN:0006-291X
1090-2104
DOI:10.1016/j.bbrc.2016.01.142