Histologic differences between primary high myopia and secondary high myopia due to congenital glaucoma

Purpose To search for histomorphometric differences between eyes with primary high myopia (PHM) or secondary high axial myopia (SHM) caused by congenital glaucoma, and non‐highly myopic eyes (NHM). Methods Histologic anterior–posterior sections were histomorphometrically examined. Results The invest...

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Veröffentlicht in:Acta ophthalmologica (Oxford, England) England), 2016-03, Vol.94 (2), p.147-153
Hauptverfasser: Jonas, Jost B., Holbach, Leonard, Panda‐Jonas, Songhomitra
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Sprache:eng
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Zusammenfassung:Purpose To search for histomorphometric differences between eyes with primary high myopia (PHM) or secondary high axial myopia (SHM) caused by congenital glaucoma, and non‐highly myopic eyes (NHM). Methods Histologic anterior–posterior sections were histomorphometrically examined. Results The investigation included 58 human globes (mean age: 61.5 ± 18.5 years; axial length: 27.3 ± 4.0 mm; range: 21.0–39.0 mm). Bruch's membrane thickness was thinner in SHM than in PHM (posterior pole: p = 0.007; parapapillary region: p = 0.007); midpoint posterior pole/equator = 0.05) and thinner in SHM than in NHM (all p  0.50). Choroidal thickness did not differ (all p ≥ 0.40) at any measurement location between SHM and PHM, and was thinner (p 
ISSN:1755-375X
1755-3768
DOI:10.1111/aos.12937