Miniaturization of homogeneous assays using fluorescence polarization

Miniaturization of homogeneous assays using fluorescence polarization

Homogeneous fluorescence-based assays are a significant development in HTS. Fluorescence polarization (FP) is emerging as an important HTS technology that reduces costs while greatly increasing throughput. Inherently suitable for miniaturization, FP has been demonstrated to run in as little as 4 μl...

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Veröffentlicht in:Drug Discovery Today 2000-06, Vol.5, p.27-32
Hauptverfasser: Sportsman, J.Richard, Leytes, Lev J.
Format: Artikel
Sprache:eng
Schlagworte:
Techniques and methods
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Zusammenfassung:Homogeneous fluorescence-based assays are a significant development in HTS. Fluorescence polarization (FP) is emerging as an important HTS technology that reduces costs while greatly increasing throughput. Inherently suitable for miniaturization, FP has been demonstrated to run in as little as 4 μl total assay volume.
ISSN:1359-6446
1878-5832
DOI:10.1016/S1359-6446(00)01496-3