High Ki67 expression is an independent good prognostic marker in colorectal cancer

AimsTo correlate Ki67 expression with outcome in colorectal cancer (CRC).MethodsKi67 labelling index (Ki67LI) was analysed by immunohistochemistry on a tissue microarray containing 1800 CRCs. The results were compared with clinicopathological and molecular parameters.ResultsKi67LI was considered low...

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Veröffentlicht in:	Journal of clinical pathology 2016-03, Vol.69 (3), p.209-214
Hauptverfasser:	Melling, Nathaniel, Kowitz, Charlotte Marie, Simon, Ronald, Bokemeyer, Carsten, Terracciano, Luigi, Sauter, Guido, Izbicki, Jakob Robert, Marx, Andreas Holger
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aged beta Catenin - analysis Breast cancer Cancer therapies Cell cycle Cell growth Cell Proliferation Chemotherapy Colorectal cancer Colorectal Neoplasms - chemistry Colorectal Neoplasms - mortality Colorectal Neoplasms - pathology Colorectal Neoplasms - therapy Female Humans Immunohistochemistry Kaplan-Meier Estimate Ki-67 Antigen - analysis Localization Lymphatic Metastasis Male Medical prognosis Metastasis Middle Aged Multivariate Analysis Neoplasm Staging Pathology Predictive Value of Tests Proportional Hazards Models Studies Surgery Time Factors Tissue Array Analysis Treatment Outcome Tumor Suppressor Protein p53 - analysis Tumors Up-Regulation Variance analysis
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