Lymphocytic choriomeningitis virus infection induced by percutaneous exposure

We report a case of acquired lymphocytic choriomeningitis virus (LCMV) infection due to an accidental percutaneous inoculation of LCMV at work. The injured worker developed a flu-like syndrome, followed by pericarditis and meningoencephalitis. Seroconversion was confirmed by ELISA. The patient made...

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Veröffentlicht in:	Occupational medicine (Oxford) 2016-03, Vol.66 (2), p.171-173
Hauptverfasser:	Aebischer, O, Meylan, P, Kunz, S, Lazor-Blanchet, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Accidents, Occupational Adult Antiviral Agents - administration & dosage Humans Lymphocytic Choriomeningitis - drug therapy Lymphocytic Choriomeningitis - etiology Lymphocytic Choriomeningitis - virology Lymphocytic choriomeningitis virus - pathogenicity Male Needlestick Injuries - virology Occupational Exposure - adverse effects Post-Exposure Prophylaxis Practice Guidelines as Topic Ribavirin - administration & dosage Treatment Outcome
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Beschreibung
Zusammenfassung:	We report a case of acquired lymphocytic choriomeningitis virus (LCMV) infection due to an accidental percutaneous inoculation of LCMV at work. The injured worker developed a flu-like syndrome, followed by pericarditis and meningoencephalitis. Seroconversion was confirmed by ELISA. The patient made a complete recovery. We review measures undertaken to prevent a similar event and propose a follow-up protocol in the event of accidental LCMV exposure.
ISSN:	0962-7480 1471-8405
DOI:	10.1093/occmed/kqv156