Enhancement of chrysogenin production in cultures of Penicillium chrysogenum by uronic acid oligosaccharides

Additions of 50 to 100 μg of acid-hydrolysed alginate oligosaccharides ml^sup -1^ and enzyme-hydrolysed pectin oligosaccharides to 24- to 48-h cultures of Penicillium chrysogenum, ATCC 9480, led to enhanced production of chrysogenin by over 30 to 40% in shaken flasks and bioreactors. Some of the oli...

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Veröffentlicht in:Biotechnology letters 2000-06, Vol.22 (11), p.931-936
Hauptverfasser: ASILONU, E, BUCKE, C, KESHAVARZ, T
Format: Artikel
Sprache:eng
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Zusammenfassung:Additions of 50 to 100 μg of acid-hydrolysed alginate oligosaccharides ml^sup -1^ and enzyme-hydrolysed pectin oligosaccharides to 24- to 48-h cultures of Penicillium chrysogenum, ATCC 9480, led to enhanced production of chrysogenin by over 30 to 40% in shaken flasks and bioreactors. Some of the oligosaccharides also promoted biomass formation but were not used as a carbon source.[PUBLICATION ABSTRACT]
ISSN:0141-5492
1573-6776
DOI:10.1023/A:1005694415666