Inhibition of eel enzymatic activities by cadmium

Inhibition of eel enzymatic activities by cadmium

The aim of the present work was to study the in vitro effect of cadmium on enzymes, such as intestinal and branchial carbonic anhydrase (CA) and Na +-K +-ATPase which play a key role in salt- and osmoregulation and acid–base balance in the teleost fish, Anguilla anguilla. Carbonic anhydrase activiti...

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Veröffentlicht in:Aquatic toxicology 2000-04, Vol.48 (4), p.561-571
Hauptverfasser: Lionetto, M.G, Giordano, M.E, Vilella, S, Schettino, T
Format: Artikel
Sprache:eng
Schlagworte:
Agnatha. Pisces
Anguilla anguilla
Animal, plant and microbial ecology
Applied ecology
Biological and medical sciences
Brackish
Cadmium
Carbonic anhydrase
Ecotoxicology, biological effects of pollution
Eel
Effects of pollution and side effects of pesticides on vertebrates
Freshwater
Fundamental and applied biological sciences. Psychology
Gills
Intestine
Marine
Na +-K +-ATPase
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Zusammenfassung:The aim of the present work was to study the in vitro effect of cadmium on enzymes, such as intestinal and branchial carbonic anhydrase (CA) and Na +-K +-ATPase which play a key role in salt- and osmoregulation and acid–base balance in the teleost fish, Anguilla anguilla. Carbonic anhydrase activities in gill and intestinal homogenates were significantly inhibited by CdCl 2, the gill CA being more sensitive to the heavy metal (IC 50 for the branchial CA=9.97±1.03×10 −6 M, IC 50 for the intestinal CA=3.64±1.03×10 −5 M, P
ISSN:0166-445X
1879-1514
DOI:10.1016/S0166-445X(99)00056-9