Neuraminidase Inhibitor-Resistant Influenza Viruses May Differ Substantially in Fitness and Transmissibility

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 2005-10, Vol.49 (10), p.4075-4084
Hauptverfasser:	Yen, Hui-Ling, Herlocher, Louise M, Hoffmann, Erich, Matrosovich, Mikhail N, Monto, Arnold S, Webster, Robert G, Govorkova, Elena A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetamides - pharmacology Amino Acid Substitution Animals Antiviral Agents Cell Line Coculture Techniques Disease Models, Animal Drug Resistance, Multiple Drug Resistance, Viral Drug Resistance, Viral - drug effects Drug Resistance, Viral - genetics Drug Resistance, Viral - physiology Drug Tolerance Enzyme Inhibitors - pharmacology Enzyme Stability - genetics Female Ferrets Genetic Variation Guanidines - pharmacology Kinetics Mutagenesis, Site-Directed Neuraminidase Neuraminidase - antagonists & inhibitors Neuraminidase - genetics Neuraminidase - metabolism Orthomyxoviridae Orthomyxoviridae - drug effects Orthomyxoviridae - enzymology Orthomyxoviridae - genetics Orthomyxoviridae - growth & development Orthomyxoviridae Infections Orthomyxoviridae Infections - transmission Oseltamivir Pyrans - pharmacology Recombination, Genetic Sialic Acids - pharmacology Temperature Virus Replication - genetics Zanamivir
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Zusammenfassung:	Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology. For an alternate route to AAC .asm.org, visit: AAC
ISSN:	0066-4804 1098-6596
DOI:	10.1128/aac.49.10.4075-4084.2005