Differential expression of alkaline phosphatase gene in proliferating primary lymphocytes and malignant lymphoid cell lines

Highlights • APase gene is upregulated specifically in mitogen activated murine B lymphocytes. • APase gene is not expressed in activated murine and human T lymphocytes and T cell lines. • Pase activity correlated with its gene expression in human myeloma cell line.

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Veröffentlicht in:Immunology letters 2016-02, Vol.170, p.37-41
Hauptverfasser: Latheef, S.A.A, Devanabanda, Mallaiah, Sankati, Swetha, Madduri, Ramanadham
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container_title Immunology letters
container_volume 170
creator Latheef, S.A.A
Devanabanda, Mallaiah
Sankati, Swetha
Madduri, Ramanadham
description Highlights • APase gene is upregulated specifically in mitogen activated murine B lymphocytes. • APase gene is not expressed in activated murine and human T lymphocytes and T cell lines. • Pase activity correlated with its gene expression in human myeloma cell line.
doi_str_mv 10.1016/j.imlet.2015.12.008
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identifier ISSN: 0165-2478
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Alkaline Phosphatase - genetics
Alkaline Phosphatase - metabolism
Alkaline phosphatase activity
Alkaline phosphatase gene expression
Allergy and Immunology
Animals
Cell Line, Tumor
Enzyme Activation
Gene Expression Regulation
Human peripheral blood lymphocytes
Humans
Lipopolysaccharide
Lymphocyte Activation - genetics
Lymphocyte Activation - immunology
Lymphocytes - immunology
Lymphocytes - metabolism
Lymphoma - genetics
Lymphoma - metabolism
Mice
Myeloma cell line
RNA, Messenger - genetics
RNA, Messenger - metabolism
Spleen - metabolism
title Differential expression of alkaline phosphatase gene in proliferating primary lymphocytes and malignant lymphoid cell lines
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