Surgery for “Long-term epilepsy associated tumors (LEATs)”: Seizure outcome and its predictors
Highlights • We studied a large cohort of “Long-term epilepsy associated tumors (LEATs).” • 105 patients with LEATs underwent surgery in our center. • At 7.5 years follow-up, 74% were seizure-free and 57% were drug-free. • Secondary generalized seizures before surgery predicts a poor seizure outcome...
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| Veröffentlicht in: | Clinical neurology and neurosurgery 2016-02, Vol.141, p.98-105 |
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| container_title | Clinical neurology and neurosurgery |
| container_volume | 141 |
| creator | Radhakrishnan, Ashalatha Abraham, Mathew Vilanilam, George Menon, Ramshekhar Menon, Deepak Kumar, Hardeep Cherian, Ajith Radhakrishnan, Neelima Kesavadas, Chandrashekharan Thomas, Bejoy Sarma, Sankara P Thomas, Sanjeev V |
| description | Highlights • We studied a large cohort of “Long-term epilepsy associated tumors (LEATs).” • 105 patients with LEATs underwent surgery in our center. • At 7.5 years follow-up, 74% were seizure-free and 57% were drug-free. • Secondary generalized seizures before surgery predicts a poor seizure outcome. • Early excision of LEATs should be advocated. |
| doi_str_mv | 10.1016/j.clineuro.2015.12.020 |
| format | Article |
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diagnosis</subject><subject>Brain Neoplasms - mortality</subject><subject>Brain Neoplasms - surgery</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Confidence intervals</subject><subject>Drug resistance</subject><subject>Epilepsy</subject><subject>Epilepsy - diagnosis</subject><subject>Epilepsy - mortality</subject><subject>Epilepsy - surgery</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Histopathology</subject><subject>Humans</subject><subject>LEATs</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neurology</subject><subject>Neurosurgery</subject><subject>Pathology</subject><subject>Predictive Value of Tests</subject><subject>Resective surgery</subject><subject>Seizure outcome</subject><subject>Seizures - diagnosis</subject><subject>Seizures - mortality</subject><subject>Seizures - surgery</subject><subject>Statistical analysis</subject><subject>Surgery</subject><subject>Survival Rate - trends</subject><subject>Treatment Outcome</subject><subject>Tumors</subject><subject>Young Adult</subject><issn>0303-8467</issn><issn>1872-6968</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNks1u1DAUhS0EokPhFSpLbMoi4TpO7IQFalWVH2kkFlPWVuxcVx6SeLATpGHVB4GX65PgMC1I3cDqbr57rs45l5ATBjkDJl5vc9O7Eefg8wJYlbMihwIekRWrZZGJRtSPyQo48KwuhTwiz2LcAgDnon5KjgohJRdNsyJ6M4drDHtqfaC3Nz_WfrzOJgwDxZ3rcRf3tI3RG9dO2NFpHnyI9HR9eX4VX93e_HxDN-i-zwGpnyfjB6Tt2FE3RboL2DkzJfw5eWLbPuKLu3lMPr-7vLr4kK0_vf94cb7OTFmXU8aENSXvtODCcs2tkWUDvEp-oG60lSi0sJobacvCFC2AlJahriSToHmp-TE5Pejugv86Y5zU4KLBvm9H9HNUTIqqqRtZyf9BeToLsknoywfo1s9hTEZ-UynTkvNEiQNlgo8xoFW74IY27BUDtRSmtuq-MLUUplihUmFp8eROftYDdn_W7htKwNkBwBTdN4dBReNwNCndgGZSnXf_vvH2gcSCOdP2X3CP8a8fFdOC2ixvs3wNqzgwkCX_BSIIwA4</recordid><startdate>20160201</startdate><enddate>20160201</enddate><creator>Radhakrishnan, Ashalatha</creator><creator>Abraham, Mathew</creator><creator>Vilanilam, George</creator><creator>Menon, Ramshekhar</creator><creator>Menon, Deepak</creator><creator>Kumar, Hardeep</creator><creator>Cherian, Ajith</creator><creator>Radhakrishnan, Neelima</creator><creator>Kesavadas, Chandrashekharan</creator><creator>Thomas, Bejoy</creator><creator>Sarma, Sankara P</creator><creator>Thomas, Sanjeev V</creator><general>Elsevier B.V</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20160201</creationdate><title>Surgery for “Long-term epilepsy associated tumors (LEATs)”: Seizure outcome and its predictors</title><author>Radhakrishnan, Ashalatha ; Abraham, Mathew ; Vilanilam, George ; Menon, Ramshekhar ; Menon, Deepak ; Kumar, Hardeep ; Cherian, Ajith ; Radhakrishnan, Neelima ; Kesavadas, Chandrashekharan ; Thomas, Bejoy ; Sarma, Sankara P ; Thomas, Sanjeev V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c484t-16fc43db636f3b3fc749035187089bf7e6b6fb3c7f42c2a0077f1eb57170b34b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age</topic><topic>Brain Neoplasms - 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| fulltext | fulltext |
| identifier | ISSN: 0303-8467 |
| ispartof | Clinical neurology and neurosurgery, 2016-02, Vol.141, p.98-105 |
| issn | 0303-8467 1872-6968 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adolescent Adult Age Brain Neoplasms - diagnosis Brain Neoplasms - mortality Brain Neoplasms - surgery Child Child, Preschool Confidence intervals Drug resistance Epilepsy Epilepsy - diagnosis Epilepsy - mortality Epilepsy - surgery Female Follow-Up Studies Histopathology Humans LEATs Male Middle Aged Neurology Neurosurgery Pathology Predictive Value of Tests Resective surgery Seizure outcome Seizures - diagnosis Seizures - mortality Seizures - surgery Statistical analysis Surgery Survival Rate - trends Treatment Outcome Tumors Young Adult |
| title | Surgery for “Long-term epilepsy associated tumors (LEATs)”: Seizure outcome and its predictors |
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