Surgery for “Long-term epilepsy associated tumors (LEATs)”: Seizure outcome and its predictors

Highlights • We studied a large cohort of “Long-term epilepsy associated tumors (LEATs).” • 105 patients with LEATs underwent surgery in our center. • At 7.5 years follow-up, 74% were seizure-free and 57% were drug-free. • Secondary generalized seizures before surgery predicts a poor seizure outcome...

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Veröffentlicht in:	Clinical neurology and neurosurgery 2016-02, Vol.141, p.98-105
Hauptverfasser:	Radhakrishnan, Ashalatha, Abraham, Mathew, Vilanilam, George, Menon, Ramshekhar, Menon, Deepak, Kumar, Hardeep, Cherian, Ajith, Radhakrishnan, Neelima, Kesavadas, Chandrashekharan, Thomas, Bejoy, Sarma, Sankara P, Thomas, Sanjeev V
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Brain Neoplasms - diagnosis Brain Neoplasms - mortality Brain Neoplasms - surgery Child Child, Preschool Confidence intervals Drug resistance Epilepsy Epilepsy - diagnosis Epilepsy - mortality Epilepsy - surgery Female Follow-Up Studies Histopathology Humans LEATs Male Middle Aged Neurology Neurosurgery Pathology Predictive Value of Tests Resective surgery Seizure outcome Seizures - diagnosis Seizures - mortality Seizures - surgery Statistical analysis Surgery Survival Rate - trends Treatment Outcome Tumors Young Adult
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Zusammenfassung:	Highlights • We studied a large cohort of “Long-term epilepsy associated tumors (LEATs).” • 105 patients with LEATs underwent surgery in our center. • At 7.5 years follow-up, 74% were seizure-free and 57% were drug-free. • Secondary generalized seizures before surgery predicts a poor seizure outcome. • Early excision of LEATs should be advocated.
ISSN:	0303-8467 1872-6968
DOI:	10.1016/j.clineuro.2015.12.020