Subtle alterations in memory systems and normal visual attention in the GAERS model of absence epilepsy

Highlights • We tested the functionality of memory systems and of sustained visual attention. • GAERS showed slower learning and weaker working memory in the Morris water maze. • In the 8-arm radial maze and the T-maze working memory was not altered in GAERS. • Procedural memory and visual attention...

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Veröffentlicht in:	Neuroscience 2016-03, Vol.316, p.389-401
Hauptverfasser:	Marques-Carneiro, J.E, Faure, J.-B, Barbelivien, A, Nehlig, A, Cassel, J.-C
Format:	Artikel
Sprache:	eng
Schlagworte:	absence epilepsy Animals Attention Deficit Disorder with Hyperactivity - etiology Choice Behavior - physiology Disease Models, Animal Epilepsy, Absence - complications learning Male Maze Learning - physiology Memory Disorders - etiology Memory, Short-Term - physiology Neurology Photic Stimulation procedural memory Psychophysics Rats Rats, Wistar Reaction Time - physiology reference memory Spatial Memory - physiology Statistics, Nonparametric visual sustained attention working memory
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Beschreibung
Zusammenfassung:	Highlights • We tested the functionality of memory systems and of sustained visual attention. • GAERS showed slower learning and weaker working memory in the Morris water maze. • In the 8-arm radial maze and the T-maze working memory was not altered in GAERS. • Procedural memory and visual attention were mostly unimpaired.
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2015.12.048