Exercise and Estrogen Make Fat Cells "Fit"

Adipose tissue inflammation links obesity and metabolic disease. Both exercise and estrogen improve metabolic health, enhance mitochondrial function, and have antiinflammatory effects. We hypothesize that there is an inverse relationship between mitochondrial function and inflammation in adipose tis...

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Veröffentlicht in:	Exercise and sport sciences reviews 2015-07, Vol.43 (3), p.172-178
Hauptverfasser:	Vieira-Potter, Victoria J, Zidon, Terese M, Padilla, Jaume
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue, White - physiology Energy Metabolism Estrogens - physiology Exercise - physiology Female Humans Inflammation - physiopathology Male Mitochondria - physiology Sex Factors
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Zusammenfassung:	Adipose tissue inflammation links obesity and metabolic disease. Both exercise and estrogen improve metabolic health, enhance mitochondrial function, and have antiinflammatory effects. We hypothesize that there is an inverse relationship between mitochondrial function and inflammation in adipose tissue and that exercise acts as an estrogen "mimetic." Explicitly, exercise may improve adipose tissue "immunometabolism" by improving mitochondrial function and reducing inflammation.
ISSN:	0091-6331 1538-3008
DOI:	10.1249/JES.0000000000000046