Primary Pulmonary Synovial Sarcoma Showing a Prolonged Survival with Multimodality Therapy

A 54-year-old man was referred to our hospital due to a mass shadow noted on a chest X-ray. Thoracoscopic lobectomy yielded a diagnosis of primary pulmonary synovial sarcoma according to the histology and SYT-SSX1 gene analyses. Five months after the thoracic surgery, he developed brain metastasis;...

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Veröffentlicht in:Internal Medicine 2016, Vol.55(4), pp.381-387
Hauptverfasser: Ogino, Hirokazu, Hanibuchi, Masaki, Takizawa, Hiromitsu, Sakiyama, Shoji, Sumitomo, Hiroyuki, Iwamoto, Seiji, Ikushima, Hitoshi, Nakajima, Kohei, Nagahiro, Shinji, Yamago, Taito, Toyoda, Yuko, Bando, Yoshimi, Nishioka, Yasuhiko
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Sprache:eng
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Zusammenfassung:A 54-year-old man was referred to our hospital due to a mass shadow noted on a chest X-ray. Thoracoscopic lobectomy yielded a diagnosis of primary pulmonary synovial sarcoma according to the histology and SYT-SSX1 gene analyses. Five months after the thoracic surgery, he developed brain metastasis; therefore, we performed resection of the brain metastatic focus followed by radiotherapy. As a local recurrence in the thoracic cavity concurrently emerged, systemic chemotherapy was also administered. These observations indicated that a multidisciplinary approach may be useful against primary pulmonary synovial sarcoma, although there is presently no established therapeutic strategy due to its rarity and highly aggressive nature.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.55.5169