Elispot Igra With Purified Protein Derivative Stimulation For Diagnosing Nontuberculous Mycobacterial Cervical Lympadenitis

Childhood cervical lymphadenitis caused by nontuberculous mycobacteria is a diagnostic challenge for the clinician. We present a new promising diagnostic method for childhood nontuberculous mycobacterial lymphadenitis. The modified T-SPOT.TB test with purified protein derivative as an additional ant...

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Veröffentlicht in:	The Pediatric infectious disease journal 2016-03, Vol.35 (3), p.349-351
Hauptverfasser:	Kontturi, Antti, Tuuminen, Tamara, Karttunen, Riitta, Salo, Eeva
Format:	Artikel
Sprache:	eng
Schlagworte:	Biopsy Case-Control Studies Child, Preschool Enzyme-Linked Immunospot Assay - methods Female Finland Humans Infant Lymph Nodes - microbiology Lymph Nodes - pathology Lymphadenitis - diagnosis Lymphadenitis - immunology Lymphadenitis - microbiology Male Mycobacterium Infections, Nontuberculous - diagnosis Mycobacterium Infections, Nontuberculous - immunology Mycobacterium Infections, Nontuberculous - microbiology Nontuberculous Mycobacteria - immunology
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Beschreibung
Zusammenfassung:	Childhood cervical lymphadenitis caused by nontuberculous mycobacteria is a diagnostic challenge for the clinician. We present a new promising diagnostic method for childhood nontuberculous mycobacterial lymphadenitis. The modified T-SPOT.TB test with purified protein derivative as an additional antigen is noninvasive with estimated sensitivity and specificity of 1.00 and 0.81, respectively.
ISSN:	0891-3668 1532-0987
DOI:	10.1097/INF.0000000000000998