Successful thrombolytic therapy for ST-elevation acute myocardial infarction in a patient with immune thrombocytopenic purpura

Thrombolytic therapy (100 mg/1.5 hours in tissue plasminogen activator ([tPA]) was given intravenously to the patient who had permenant chest pain and ST-segment elevation on surface ECG despite intravenous (IV) morphine and IV nitroglycerin. Together with the failure of bone marrow megakaryocytes t...

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Veröffentlicht in:	The American journal of emergency medicine 2016-02, Vol.34 (2), p.345.e1-345.e3
Hauptverfasser:	Koklu, Erkan, MD, Kus, Gorkem, MD, Yuksel, Isa Oner, MD, Kucukseymen, Selcuk, MD, Arslan, Sakir, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Bone marrow Cardiology Coronary Angiography Electrocardiography Emergency Emergency medical care Heart attacks Humans Male Myocardial infarction Myocardial Infarction - diagnosis Myocardial Infarction - drug therapy Myocardial Infarction - etiology Platelet Aggregation Inhibitors - therapeutic use Purpura, Thrombocytopenic, Idiopathic - complications Purpura, Thrombocytopenic, Idiopathic - drug therapy Thrombolytic Therapy - methods Veins & arteries
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Zusammenfassung:	Thrombolytic therapy (100 mg/1.5 hours in tissue plasminogen activator ([tPA]) was given intravenously to the patient who had permenant chest pain and ST-segment elevation on surface ECG despite intravenous (IV) morphine and IV nitroglycerin. Together with the failure of bone marrow megakaryocytes to produce thrombocytes, shortening of the thrombocytes' lifespan in circulation results in a decrease in the total number of thrombocytes as the disease progresses.
ISSN:	0735-6757 1532-8171
DOI:	10.1016/j.ajem.2015.06.027