Prognostic value of skin lesions in sarcoidosis: clinical and histopathological clues

Background Although tremendous advances have been made, a significant gap exists between the vast knowledge accumulated concerning sarcoidosis in recent years and our understanding of this disease. Objective Describe the main clinical and histopathological findings associated with cutaneous sarcoidosis and to investigate the relationship of these skin lesions with systemic involvement. Materials and Methods Aretrospective review of 41 patients who were diagnosed with cutaneous sarcoidosis was done. Results The study included 34 females and 7 males. Systemic disease occurred frequently in patients with lupus pernio and nodulo-plaque type lesions. Systemic symptoms were observed more commonly in patients with raised serum ACE levels (84.6% vs . 40%; p