Evaluation of the 3D spatial distribution of the Calcium/Phosphorus ratio in bone using computed-tomography dual-energy analysis

Highlights • We test a CT technique for Ca/P ratio assessment in bone apatite. • We extend the technique for its application to intact bone. • Differences in Ca/P ratio are found between healthy and osteoporotic bones. • Potential in vitro and in vivo applications of the technique are described....

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Veröffentlicht in:	Physica medica 2016-01, Vol.32 (1), p.162-168
Hauptverfasser:	Hadjipanteli, A, Kourkoumelis, N, Fromme, P, Huang, J, Speller, R.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apatites - chemistry Bone Bone and Bones - diagnostic imaging Bone composition Bone Density Ca/P ratio Calcium - chemistry Collagen - chemistry Dual energy analysis Female Imaging, Three-Dimensional Inflammation Osteoporosis Osteoporosis - diagnostic imaging Phosphorus - chemistry Rabbits Radiology Reproducibility of Results Tomography, X-Ray Computed
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Beschreibung
Zusammenfassung:	Highlights • We test a CT technique for Ca/P ratio assessment in bone apatite. • We extend the technique for its application to intact bone. • Differences in Ca/P ratio are found between healthy and osteoporotic bones. • Potential in vitro and in vivo applications of the technique are described.
ISSN:	1120-1797 1724-191X
DOI:	10.1016/j.ejmp.2015.11.004