Analysis of delayed TBE-vaccine booster after primary vaccination

Analysis of delayed TBE-vaccine booster after primary vaccination

An open, uncontrolled single centre study was conducted in the Travel Clinic at the Military Hospital, Brussels. Eighty-eight subjects were recruited who had a primary series of tick-borne encephalitis (TBE) vaccine more than 5 years ago and who never received a booster dose afterwards. Response rat...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of travel medicine 2016-02, Vol.23 (2), p.tav020-tav020
Hauptverfasser: Aerssens, Annelies, Cochez, Christel, Niedrig, Matthias, Heyman, Paul, Kühlmann-Rabens, Ilona, Soentjens, Patrick
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Belgium
Encephalitis
Encephalitis Viruses, Tick-Borne - immunology
Encephalitis, Tick-Borne - prevention & control
Enzyme-Linked Immunosorbent Assay
Female
Hospitals, Military
Humans
Immunization
Immunization Schedule
Immunization, Secondary
Immunoglobulins
Male
Middle Aged
Military Medicine
Neutralization Tests
Outcome Assessment (Health Care)
Travel Medicine
Vaccines
Viral Vaccines - immunology
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:An open, uncontrolled single centre study was conducted in the Travel Clinic at the Military Hospital, Brussels. Eighty-eight subjects were recruited who had a primary series of tick-borne encephalitis (TBE) vaccine more than 5 years ago and who never received a booster dose afterwards. Response rate after booster vaccination was very high: 84 out of 88 subjects (95.5%) had neutralizing antibodies on plaque reduction neutralization test and all (100%) had IgG antibodies on ELISA, on Day 21–28 after booster vaccination. This study adds valuable information to the common situation of delayed booster interval. The results of our study indicate that in young healthy travellers (
ISSN:1195-1982
1708-8305
DOI:10.1093/jtm/tav020