Genetic polymorphisms and mutation rates of 27 Y-chromosomal STRs in a Han population from Guangdong Province, Southern China

Highlights • The haplotypes of 27 Y-STR loci of 1007 unrelated males from a Chinese Han population were typed with Yfiler® Plus system. • 1033 father–son pairs were genotyped and the average mutation rate for the 27 Y-STR loci is relatively high. • Population relationships were analyzed by compariso...

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Veröffentlicht in:	Forensic science international : genetics 2016-03, Vol.21, p.5-9
Hauptverfasser:	Wang, Ying, Zhang, Yong-ji, Zhang, Chu-chu, Li, Ran, Yang, Yang, Ou, Xue-ling, Tong, Da-yue, Sun, Hong-yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Asian Continental Ancestry Group - genetics China Chromosomes, Human, Y DNA Copy Number Variations Ethnic Groups - genetics Forensic Genetics - methods Gene Frequency Genetic Variation Genetics, Population Haplotype Haplotypes Humans Male Microsatellite Repeats Mutation Mutation Rate Pathology Polymorphism, Genetic Rapidly mutating Y-STRs Y-chromosomal short tandem repeats Yfiler® Plus system
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Zusammenfassung:	Highlights • The haplotypes of 27 Y-STR loci of 1007 unrelated males from a Chinese Han population were typed with Yfiler® Plus system. • 1033 father–son pairs were genotyped and the average mutation rate for the 27 Y-STR loci is relatively high. • Population relationships were analyzed by comparison with 19 other worldwide populations.
ISSN:	1872-4973 1878-0326
DOI:	10.1016/j.fsigen.2015.09.013