Ipsilateral cortical motor desynchronisation is reduced in Benign Epilepsy with Centro-Temporal Spikes

Ipsilateral cortical motor desynchronisation is reduced in Benign Epilepsy with Centro-Temporal Spikes

Highlights • On a MEG motor task in children with Benign Epilepsy with Centro-Temporal Spikes (BECTS) we found reduced ipsilateral cortical desynchronisation. • This reduced ipsilateral cortical desynchronisation was linked to poorer motor skills and more recent seizures. • Our findings suggest disr...

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Veröffentlicht in:Clinical neurophysiology 2016-02, Vol.127 (2), p.1147-1156
Hauptverfasser: Brindley, Lisa M, Koelewijn, Loes, Kirby, Amanda, Williams, Natalie, Thomas, Marie, te Water-Naudé, Johann, Gibbon, Frances, Muthukumaraswamy, Suresh, Singh, Krish D, Hamandi, Khalid
Format: Artikel
Sprache:eng
Schlagworte:
Action Potentials - physiology
Adolescent
BECTS
Brain Waves - physiology
Child
Cohort Studies
Cortical Synchronization - physiology
Development
Epilepsy, Rolandic - diagnosis
Epilepsy, Rolandic - physiopathology
Female
Humans
Magnetoencephalography - methods
Male
MEG
Motor Cortex - physiopathology
Movement
Neurology
Oscillations
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Zusammenfassung:Highlights • On a MEG motor task in children with Benign Epilepsy with Centro-Temporal Spikes (BECTS) we found reduced ipsilateral cortical desynchronisation. • This reduced ipsilateral cortical desynchronisation was linked to poorer motor skills and more recent seizures. • Our findings suggest disrupted inter-hemispheric interactions during motor control in BECTS.
ISSN:1388-2457
1872-8952
DOI:10.1016/j.clinph.2015.08.020