Body Composition Changes in Adult Females after Lifestyle Intervention Are Influenced by the NYD-SP18 Variant

The study focuses on the analysis of the possible relationship between a common NYD-SP18 (rs6971091, G>A) gene polymorphism and weight loss after lifestyle intervention (combined dietary intake and physical activity) in overweight/obese females. We genotyped 139 unrelated non-diabetic Czech femal...

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Veröffentlicht in:	Central European journal of public health 2015-11, Vol.23 Suppl (Supplement), p.S19-S22
Hauptverfasser:	Suchánek, Pavel, Lánská, Věra, Hubáček, Jaroslav Alois
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Aged Automation Blood pressure Body composition Body Composition - genetics Czech Republic Diabetes Diet Diet, Reducing Enzymes Exercise Female Genes Genotype GTPase-Activating Proteins - genetics Heart Humans Intervention Life Style Lifestyles Metabolic disorders Middle Aged Obesity Obesity - genetics Obesity - prevention & control Overweight - genetics Overweight - prevention & control Physical fitness Polymorphism, Single Nucleotide - genetics Studies Weight control Weight Loss - genetics
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Zusammenfassung:	The study focuses on the analysis of the possible relationship between a common NYD-SP18 (rs6971091, G>A) gene polymorphism and weight loss after lifestyle intervention (combined dietary intake and physical activity) in overweight/obese females. We genotyped 139 unrelated non-diabetic Czech females (49.5 ± 13.3 years, average BMI at baseline 32.2 ± 4.6 kg/m². Biochemical and anthropometrical measurements were performed before and after ten weeks of lifestyle intervention. Overweight/obese female carriers of the NYD-SP18 rs6971091 GG genotype exhibited a more beneficial response to the intensive lifestyle intervention than others.
ISSN:	1210-7778 1803-1048
DOI:	10.21101/cejph.a4105