Biosynthesis of polyketides by trans-AT polyketide synthases

This review discusses the biosynthesis of natural products that are generated by trans-AT polyketide synthases, a family of catalytically versatile enzymes that represents one of the major group of proteins involved in the production of bioactive polyketides. The article includes 609 references and...

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Veröffentlicht in:	Natural product reports 2016-02, Vol.33 (2), p.231-316
Hauptverfasser:	Helfrich, Eric J N, Piel, Jörn
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Products - metabolism Humans Molecular Structure Polyketide Synthases - metabolism Polyketides - chemistry Polyketides - metabolism
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	This review discusses the biosynthesis of natural products that are generated by trans-AT polyketide synthases, a family of catalytically versatile enzymes that represents one of the major group of proteins involved in the production of bioactive polyketides. The article includes 609 references and covers the literature from 2009 through June 2015.
ISSN:	0265-0568 1460-4752
DOI:	10.1039/c5np00125k