Glycoyessotoxin A, a New Yessotoxin Derivative from Cultures of Protoceratium reticulatum
The dinoflagellate Protoceratium reticulatum produces toxins of the yessotoxin group currently included in the diarrhetic shellfish poisoning class. In this paper we report on the isolation and structural elucidation of a 32-arabinoside of yessotoxin, G-YTXA (2), obtained from laboratory cultures of...
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Veröffentlicht in: | Journal of natural products (Washington, D.C.) D.C.), 2005-03, Vol.68 (3), p.420-422 |
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creator | SOUTO, María L. FERNáNDEZ, Jose J. FRANCO, José M. PAZ, Beatriz GIL, Laura V. NORTE, Manuel |
description | The dinoflagellate Protoceratium reticulatum produces toxins of the yessotoxin group currently included in the diarrhetic shellfish poisoning class. In this paper we report on the isolation and structural elucidation of a 32-arabinoside of yessotoxin, G-YTXA (2), obtained from laboratory cultures of P. reticulatum (strain GG1AM) that possesses a pentose unit, beta-arabinofuranose, as a side chain. |
doi_str_mv | 10.1021/np040164j |
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In this paper we report on the isolation and structural elucidation of a 32-arabinoside of yessotoxin, G-YTXA (2), obtained from laboratory cultures of P. reticulatum (strain GG1AM) that possesses a pentose unit, beta-arabinofuranose, as a side chain.</description><identifier>ISSN: 0163-3864</identifier><identifier>EISSN: 1520-6025</identifier><identifier>DOI: 10.1021/np040164j</identifier><identifier>PMID: 15787449</identifier><identifier>CODEN: JNPRDF</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Animals ; Arabinose - analogs & derivatives ; Arabinose - chemistry ; Biological and medical sciences ; Dinoflagellida - chemistry ; Ethers, Cyclic - chemistry ; Ethers, Cyclic - isolation & purification ; Ethers, Cyclic - pharmacology ; Marine ; Marine Toxins - chemistry ; Marine Toxins - isolation & purification ; Marine Toxins - pharmacology ; Medical sciences ; Molecular Structure ; Oxocins - chemistry ; Oxocins - isolation & purification ; Oxocins - pharmacology ; Plant poisons toxicology ; Toxicology</subject><ispartof>Journal of natural products (Washington, D.C.), 2005-03, Vol.68 (3), p.420-422</ispartof><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16658151$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15787449$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SOUTO, María L.</creatorcontrib><creatorcontrib>FERNáNDEZ, Jose J.</creatorcontrib><creatorcontrib>FRANCO, José M.</creatorcontrib><creatorcontrib>PAZ, Beatriz</creatorcontrib><creatorcontrib>GIL, Laura V.</creatorcontrib><creatorcontrib>NORTE, Manuel</creatorcontrib><title>Glycoyessotoxin A, a New Yessotoxin Derivative from Cultures of Protoceratium reticulatum</title><title>Journal of natural products (Washington, D.C.)</title><addtitle>J. Nat. Prod</addtitle><description>The dinoflagellate Protoceratium reticulatum produces toxins of the yessotoxin group currently included in the diarrhetic shellfish poisoning class. In this paper we report on the isolation and structural elucidation of a 32-arabinoside of yessotoxin, G-YTXA (2), obtained from laboratory cultures of P. reticulatum (strain GG1AM) that possesses a pentose unit, beta-arabinofuranose, as a side chain.</description><subject>Animals</subject><subject>Arabinose - analogs & derivatives</subject><subject>Arabinose - chemistry</subject><subject>Biological and medical sciences</subject><subject>Dinoflagellida - chemistry</subject><subject>Ethers, Cyclic - chemistry</subject><subject>Ethers, Cyclic - isolation & purification</subject><subject>Ethers, Cyclic - pharmacology</subject><subject>Marine</subject><subject>Marine Toxins - chemistry</subject><subject>Marine Toxins - isolation & purification</subject><subject>Marine Toxins - pharmacology</subject><subject>Medical sciences</subject><subject>Molecular Structure</subject><subject>Oxocins - chemistry</subject><subject>Oxocins - isolation & purification</subject><subject>Oxocins - pharmacology</subject><subject>Plant poisons toxicology</subject><subject>Toxicology</subject><issn>0163-3864</issn><issn>1520-6025</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0MtOwzAQBVALgaA8FvwA8gZWBPx2vETlKRWoRBGwilxnIhmSptgOtH9PpBbYzEj3Hs1iEDqk5IwSRs9ncyIIVeJ9Aw2oZCRThMlNNOgznvFciR20G-M7IYQTI7fRDpU610KYAXq7qZeuXUKMbWoXfoYvTrHFD_CN3_6zSwj-yyb_BbgKbYOHXZ26ABG3FR6HHjkIfd01OEDyrqtt6pp9tFXZOsLBeu-h5-uryfA2Gz3e3A0vRplnWqfMQW64pRKgFFbrfpAyt8QwwRh3WhpWMWdzNwXFp4TlpSsFmMpwXVEmcsX30Mnq7jy0nx3EVDQ-OqhrO4O2iwXViklKTA-P1rCbNlAW8-AbG5bF7zN6cLwGNjpbV8HOnI__TimZU0l7l62cjwkWf70NH4XSXMtiMn4qXl_u6YgaXRj-A_AXfVs</recordid><startdate>20050301</startdate><enddate>20050301</enddate><creator>SOUTO, María L.</creator><creator>FERNáNDEZ, Jose J.</creator><creator>FRANCO, José M.</creator><creator>PAZ, Beatriz</creator><creator>GIL, Laura V.</creator><creator>NORTE, Manuel</creator><general>American Chemical Society</general><general>American Society of Pharmacognosy</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>8FD</scope><scope>C1K</scope><scope>F1W</scope><scope>FR3</scope><scope>H95</scope><scope>H97</scope><scope>H99</scope><scope>L.F</scope><scope>L.G</scope><scope>P64</scope></search><sort><creationdate>20050301</creationdate><title>Glycoyessotoxin A, a New Yessotoxin Derivative from Cultures of Protoceratium reticulatum</title><author>SOUTO, María L. ; FERNáNDEZ, Jose J. ; FRANCO, José M. ; PAZ, Beatriz ; GIL, Laura V. ; NORTE, Manuel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i277t-ce893a15eed4a77d4a0d8a0924223c7592f2ca8cbe63b028dcd4e9f937f124863</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Animals</topic><topic>Arabinose - analogs & derivatives</topic><topic>Arabinose - chemistry</topic><topic>Biological and medical sciences</topic><topic>Dinoflagellida - chemistry</topic><topic>Ethers, Cyclic - chemistry</topic><topic>Ethers, Cyclic - isolation & purification</topic><topic>Ethers, Cyclic - pharmacology</topic><topic>Marine</topic><topic>Marine Toxins - chemistry</topic><topic>Marine Toxins - isolation & purification</topic><topic>Marine Toxins - pharmacology</topic><topic>Medical sciences</topic><topic>Molecular Structure</topic><topic>Oxocins - chemistry</topic><topic>Oxocins - isolation & purification</topic><topic>Oxocins - pharmacology</topic><topic>Plant poisons toxicology</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SOUTO, María L.</creatorcontrib><creatorcontrib>FERNáNDEZ, Jose J.</creatorcontrib><creatorcontrib>FRANCO, José M.</creatorcontrib><creatorcontrib>PAZ, Beatriz</creatorcontrib><creatorcontrib>GIL, Laura V.</creatorcontrib><creatorcontrib>NORTE, Manuel</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Engineering Research Database</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>ASFA: Marine Biotechnology Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Marine Biotechnology Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Journal of natural products (Washington, D.C.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SOUTO, María L.</au><au>FERNáNDEZ, Jose J.</au><au>FRANCO, José M.</au><au>PAZ, Beatriz</au><au>GIL, Laura V.</au><au>NORTE, Manuel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Glycoyessotoxin A, a New Yessotoxin Derivative from Cultures of Protoceratium reticulatum</atitle><jtitle>Journal of natural products (Washington, D.C.)</jtitle><addtitle>J. Nat. Prod</addtitle><date>2005-03-01</date><risdate>2005</risdate><volume>68</volume><issue>3</issue><spage>420</spage><epage>422</epage><pages>420-422</pages><issn>0163-3864</issn><eissn>1520-6025</eissn><coden>JNPRDF</coden><abstract>The dinoflagellate Protoceratium reticulatum produces toxins of the yessotoxin group currently included in the diarrhetic shellfish poisoning class. In this paper we report on the isolation and structural elucidation of a 32-arabinoside of yessotoxin, G-YTXA (2), obtained from laboratory cultures of P. reticulatum (strain GG1AM) that possesses a pentose unit, beta-arabinofuranose, as a side chain.</abstract><cop>Washington, DC</cop><cop>Glendale, AZ</cop><pub>American Chemical Society</pub><pmid>15787449</pmid><doi>10.1021/np040164j</doi><tpages>3</tpages></addata></record> |
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subjects | Animals Arabinose - analogs & derivatives Arabinose - chemistry Biological and medical sciences Dinoflagellida - chemistry Ethers, Cyclic - chemistry Ethers, Cyclic - isolation & purification Ethers, Cyclic - pharmacology Marine Marine Toxins - chemistry Marine Toxins - isolation & purification Marine Toxins - pharmacology Medical sciences Molecular Structure Oxocins - chemistry Oxocins - isolation & purification Oxocins - pharmacology Plant poisons toxicology Toxicology |
title | Glycoyessotoxin A, a New Yessotoxin Derivative from Cultures of Protoceratium reticulatum |
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