Glycoyessotoxin A, a New Yessotoxin Derivative from Cultures of Protoceratium reticulatum

The dinoflagellate Protoceratium reticulatum produces toxins of the yessotoxin group currently included in the diarrhetic shellfish poisoning class. In this paper we report on the isolation and structural elucidation of a 32-arabinoside of yessotoxin, G-YTXA (2), obtained from laboratory cultures of...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2005-03, Vol.68 (3), p.420-422
Hauptverfasser:	SOUTO, María L., FERNáNDEZ, Jose J., FRANCO, José M., PAZ, Beatriz, GIL, Laura V., NORTE, Manuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arabinose - analogs & derivatives Arabinose - chemistry Biological and medical sciences Dinoflagellida - chemistry Ethers, Cyclic - chemistry Ethers, Cyclic - isolation & purification Ethers, Cyclic - pharmacology Marine Marine Toxins - chemistry Marine Toxins - isolation & purification Marine Toxins - pharmacology Medical sciences Molecular Structure Oxocins - chemistry Oxocins - isolation & purification Oxocins - pharmacology Plant poisons toxicology Toxicology
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Zusammenfassung:	The dinoflagellate Protoceratium reticulatum produces toxins of the yessotoxin group currently included in the diarrhetic shellfish poisoning class. In this paper we report on the isolation and structural elucidation of a 32-arabinoside of yessotoxin, G-YTXA (2), obtained from laboratory cultures of P. reticulatum (strain GG1AM) that possesses a pentose unit, beta-arabinofuranose, as a side chain.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np040164j