Difference in white matter microstructure in differential diagnosis of normal pressure hydrocephalus and Alzheimer's disease
Highlights • Compared to AD, NPH is considered to be potentially reversible cause of dementia. • There are WM microstructure alterations in NPH as compared to AD and controls. • Findings support the utility of non-invasive DTI in differential diagnosis of NPH.
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| Veröffentlicht in: | Clinical neurology and neurosurgery 2016-01, Vol.140, p.52-59 |
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| container_title | Clinical neurology and neurosurgery |
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| creator | Hořínek, Daniel Štěpán-Buksakowska, Irena Szabó, Nikoletta Erickson, Bradley J Tóth, Eszter Šulc, Vlastimil Beneš, Vladimir Vrána, Jiří Hort, Jakub Nimsky, Christopher Mohapl, Milan Roček, Miloslav Vécsei, László Kincses, Zsigmond Tamás |
| description | Highlights • Compared to AD, NPH is considered to be potentially reversible cause of dementia. • There are WM microstructure alterations in NPH as compared to AD and controls. • Findings support the utility of non-invasive DTI in differential diagnosis of NPH. |
| doi_str_mv | 10.1016/j.clineuro.2015.11.010 |
| format | Article |
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| ispartof | Clinical neurology and neurosurgery, 2016-01, Vol.140, p.52-59 |
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| source | MEDLINE; Access via ScienceDirect (Elsevier); ProQuest Central UK/Ireland |
| subjects | Aged Aged, 80 and over Alzheimer Disease - diagnosis Alzheimer Disease - pathology Alzheimer's disease Anisotropy Diagnosis, Differential Diffusion Tensor Imaging - methods DTI Female Hospitals Humans Hydrocephalus, Normal Pressure - diagnosis Hydrocephalus, Normal Pressure - pathology Male Microstructure Middle Aged MRI Neurology Neurosurgery Normal pressure hydrocephalus Older people Pathology Registration Studies TBSS White matter White Matter - pathology |
| title | Difference in white matter microstructure in differential diagnosis of normal pressure hydrocephalus and Alzheimer's disease |
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